Beyond the guidelines on ending this flippin lockdown, there is a fair bit of news and even some good news. Let’s start with the good news.
First, the clinical trial of Remdesivir, from Gilead, has proven successful. You can read more here.
Second, a trial of Pluristem Theraputics, Inc.’s allogenic placental expanded (PLX) cells is now underway in the U.S. Seven patients at high risk of death in Israel were treated with it, and all survived. It is worth noting that the treatment may suppress or reverse the over-activation of the immune system that appears to be the cause of death in a number of victims.
While the study is from China (trust nothing, verify the everliving out of it), it is safe to go outside and stay there. You are far more likely to get it, and for multiple infections to occur if you are inside. I will echo a number of others who said ‘No duh, closing parks, beaches, etc. was fracking stupid’ and I will add that it was done by power hungry fascists who need to be removed from office ASAP.
In potentially good news, the CDC is looking at the universal testing results from a men’s shelter in Boston. A small number of positives led to the decision to do a universal test, which resulted in 146 of 397 people tested being confirmed as infected — and none of the 146 were symptomatic. Seriously, go read this as it turns a lot of the CDC/NIAIC/Etc. assumptions on their head. False assumptions lead to bad guidelines and operations. Correcting that is imperative, for both biomedical and political reasons.
In more neutral news, it appears that obesity may significantly increase your chance of becoming severely ill with COVID-19, particularly in younger to middle-aged people. I will be interested in watching to see what linkage this has with the reports that glucose metabolism (and diabetes) may play an important part in that over-stimulation of the immune system (cytokine storms) mentioned earlier. Certain types of diabetes are often linked to obesity. If COVID-19 and certain flus are indeed causing deaths by cytokine storms, understanding the mechanism is crucial to countering.
Again, it will be at least a year before we have the data and answers we need. A lot of good research has begun, and preliminary studies are not only helping shape treatment (and response), but are identifying and refining areas of future research and development. May I highly suggest not trusting media reports on the research: it is often flat out (deliberately in some cases) wrong, as I pointed out yesterday. Go to the papers, read the abstract, and on short papers take the time to read the entire publication. It is well worth the time.
I will also say that the continued war on Hydroxychloroquin is disgusting at best. The people behind this, and who actively push it, are doing a tremendous disservice and frankly should be held accountable for it. They would literally, not figuratively, rather people die than to admit that it has been shown to be effective in a number of cases. They continue to ignore as much as possible that an American study, the results of which were presented to the CDC in 2005 (link in previous updates), showed that it was effective against ALL covids. This active bit of stupidity needs to have legal consequences, as well as social.
In conclusion, don’t let the MSM wind you up or be your main source of info. When it comes to false information, they lead the pack.
Since the media isn’t going to say it, once again, COVID-19 is not Capt. Tripps. It is not the flu or a cold. Chill, distance, and use good hygiene. STOP THE PANIC!
Also, a reminder once again: if you are sick or think you are sick, DO NOT GO TO WORK OR TO VISIT PEOPLE. Stay the frack home. Don’t be Stupid, go to work/out, and insist on getting up close and personal to everyone you meet. Yes, Stupid is capitalized as I work with Stupid, who did just that. Don’t be Stupid.
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If you suspect you have COVID-19 or have been exposed: call your state health department and work with them so that you can be dealt with in a way that minimizes the chance of spreading the virus to those helping you and to the general public. Can’t get them? Call your local department or see if your health service has online/telemedicine screening set up; or see if one who has will let you use it even if you are not in their network. Do not go out in public, and don’t go to an ER or other facility without calling ahead. Be smart.
Use the interactive graphic to keep track of things. Is COVID19 an epidemic? Yes. Is it a Pandemic? Yes. Is there need for panic? NO. HELL NO. Should you be paying attention? Yes. Hell yes. Should you be preparing? Yes, better late than never. And good luck finding/getting stuff.
Want to avoid catching COVID19 here in the U.S.? Wash your flippin hands frequently, wash them thoroughly every time you use the bathroom, then follow with hand sanitizer after every washing, use hand sanitizer liberally when you can’t wash on a regular basis. Cover your mouth and nose when you sneeze, and stay away from those who don’t. Also, keep your bugger hooks out of/away from your eyes, nose, and mouth. Do NOT shake hands with anyone, and avoid touching or being touched by strangers. Or your strange friends.
Avoid travel if at all possible. If you have to travel, or go out for any reason, use lots of hand sanitizer and go to full flu protocols. If you have to use a public restroom, take full precautions including using paper towels and such to handle faucets, doors,etc. Believe it or not, this was highly recommended before now, and major grocery chains have long told employees to use those practices to avoid getting or spreading colds, flu, etc. Not many actually do it, but…
If you own a business, make sure your employees know the above protocols. Have someone who refuses to wash their hands or otherwise follow the protocols? Talk to them, write them up, and if necessary fire them as they now pose a risk of infection to you and your customers. Extreme? Yes, but while the CDC and others are working to slow it down, odds are it is already here and could hit hard and fast. Prepare for the worst and hope for the best.
I want to reiterate that there is no need for panic, but there is a strong need to be alert, be informed, and be prepared.
Good Sources Of Information On COVID-19
Instapundit (no longer doing roundups, but great articles from Glenn and his team)
South China Morning Post (decent, some salt may be needed)
Business Insider (decent, even if they did fall for some lies about Trump)
New England Journal of Medicine
Additional link to Johns Hopkins
More to come
Local Independent Businesses That Need Your Support
Oaken Barrel (Twitter at @OakenBarrel)
More to come
Other COVID19/COVID-19/2019-nCoV articles:
COVID-19 13Mar20 The Game Of Loads And Vectors Gets Real For America
COVID-19 9Mar20 The Game Of Loads And Vectors
COVID-19 7Mar20 How To Do It Right If You Have/Have Been Exposed To COVID-19
Quick Additional Thoughts On The Bureaucracy
COVID-19 28Feb20 Reasons To Hope, Reasons To Fear
COVID-19 A Plea To The Politicians (And Media)
COVID19 The Situation In China Gets Even Weirder
COVID19 24Feb20 Raising DEFCON
COVID19 21Feb20: Just Look At The Blooms Dear
Update & Quick Thoughts On Preparedness
Some Quick Thoughts On Coronavirus 2019-nCoV